Search Results
##search.searchResults.foundPlural##
-
Biological Activity of Der p 1 and Der f 1 in Allergic Asthma and Their Contribution in Inflammation and the Role of Anti-inflammation in Allergic Asthma
Asthma is a disease marked by chronic inflammation of the airways, with indications including wheezing, shortness of breath, and/or cough. As reported by GINA, the global prevalence of asthma is 1-18%. One type of...Julian
,
Anna Rozaliyani
,
Heri Wibowo
,
Triya Damayanti
-
Pharmacophore Modeling, Molecular Docking, and ADMET Approach for Identification of Anti-Cancer Agents Targeting the C-Jun N-Terminal Kinase (JNK) Protein
One of the most prevalent cancers in Indonesia is breast cancer, based on Indonesia's pathological-based registration.   Breast cancer is a complex, heterogeneous disease classified into...Nur Ayu Ramadanti
,
Linda Erlina
,
Rafika Indah Paramita
,
Aryo Tedjo
,
Fadillah Fadillah
,
Surya Dwira
-
Gastrointestinal Dysfunction after Traumatic Brain Injury: Mechanisms Linking The Gut, Inflammation, and the HPA Axis
Traumatic brain injury (TBI) is a major global health problem that often leads to systemic complications beyond neurological damage, notably gastrointestinal (GI) dysfunction. The mechanisms linking TBI to GI...Dwi Hastuti
,
Sri Widia A Jusman
,
Reni Paramita
-
Identification of Antiviral Compounds against Hepatitis C Virus (HCV) targeting NS3 Protein by Pharmacophore Modeling, Molecular Docking, and ADMET Approach
Hepatitis C Virus (HCV) is a world health problem. HCV infection is initiated by various structural and non-structural proteins. The HCV NS3 protein has an important function in viral replication. The N-terminal...Ratih Rahayu
,
Linda Erlina
,
Suratno Lulut Ratnoglik
,
Andi Yasmon
,
Fadilah
,
Rafika Indah Paramita
-
Mediastinal Tumor Thymoma Type B1 T4N2M1B Stage IVB with Multimodality Therapy
The incidence of thymoma increases with age, generally occurs in the 40-60s. Thymoma cases are rare at a young age. The prevalence of thymoma at a young age is very small at 0.6 – 5% of all thymoma cases. Thymoma...Muhammad Zakki Al-Fajri
,
Sabrina Ermayanti
,
Afriani Afriani
-
The Spectrum of Severity: Clinical and Hematological Markers in Jakarta’s COVID-19 Patients
Jakarta, a densely populated megacity with high hybrid immunity, presents a unique epidemiological landscape for COVID-19. Understanding the clinical and hematological markers in this context is vital for improving...Erlin Listiyaningsih
,
Shinta Dewi Permata Sari
,
Dewi Martalena
,
Wawang Sukarya
-
Ligand Based Pharmacophore Modelling, Virtual Screening, Molecular Docking, and ADMETOX of Natural Compounds as Antibiotic Candidates against Urinary Tract Infections (UTI)
The use of antibiotic drugs requires close supervision that patients take antibiotics according to the rules. Irregular antibiotic use led to increased ADR cases (Antibiotic Drug-resistant). ADR is when an individual...Windy Dwininda
,
Linda Erlina
,
Rafika Indah Paramita
,
Fadillah Fadillah
,
Surya Dwira
,
Jaka Fajar Fatriansyah
-
Structure-Based Virtual Screening and Molecular Docking on the Indonesian Herbal Compound as a Promising Insulin Receptor (INSR) Inhibitor to Suppress Tumor Growth
A healthy cell maintains a homeostasis condition of glucose level, whereas cancer cells do not. Increased glucose uptake is a hallmark of cancer cells that helps them survive, proliferate, and spread. INSR is one of...Veronica Hesti Candraningrum
,
Linda Erlina
,
Rafika Indah Paramita
,
Fadillah Fadillah
,
Surya Dwira
,
Jaka Fajar Fatriansyah
-
Effect of Coriander (Coriandrum sativum Lour) Seed-Ethanol Extract on Spermatozoa Quality in Alloxan-Induced Male Rats
Coriander fruit ( Coriandrum sativum Lour) has long been used and utilized by humans as a medicine to lower blood sugar levels. This study aimed to test the ethanol extract of coriander ( Coriandrum sativum Lour)...Irza Haicha Pratama
,
Neka Cahyanda Putri
,
Nuryani Nainggolan
,
Ok Yurizal
-
Effects of Radiation on the Histology of the Tongue and Lip Mucosa in Rats : Preliminary Research
The tongue and lip mucosa, as tissues with high cell proliferation rates, are highly susceptible to injury caused by ionizing radiation. This study aimed to evaluate histological changes in the tongue and lip mucosa...Sagita Yudha
,
Aisyah Elliyanti
,
Eti Yerizel
,
Sukri Rahman
-
Molecular Insights into Acne Vulgaris: A Multi-Omics Approach Towards Precision Medicine
Acne vulgaris is a common dermatological disorder that significantly impacts quality of life, yet its complex pathogenesis remains incompletely understood, contributing to the variability in clinical presentation and...Hartanti Dian Ikawati
,
Fadilah
,
Fitria Agustina
-
In Silico Evaluation of Natural Compounds as Dual Inhibitors of Exotoxin A and LasB (Elastase) Virulence Proteins in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen whose virulence is largely mediated by Exotoxin A and LasB (elastase), making them promising anti-virulence drug targets. This study aimed to evaluate the...Andrias Bayu Fariska
,
Linda Erlina
,
Ade Arsianti
,
Aryo Tedjo
-
Molecular Simulation for Screening Bioactive Compounds as Potential Candidate for Alzheimer’s Disease
Alzheimer’s disease is one of the neurodegenerative diseases that afflict the elderly. One of the symptoms is a loss cognitive ability due to neuronal death caused by amyloid plaque accumulation. Alzheimer’s...Immanuelle Kezia
,
Linda Erlina
,
Ninik Mudjihartini
,
Fadilah Fadilah
-
Exploring the Chemopreventive Potential of Soybean Phytochemicals Targeting BRCA1 Protein: A Molecular Docking Study
Breast cancer remains a significant cause of cancer-related mortality among women globally, highlighting the importance for preventive strategies targeting early molecular events. BRCA1 plays a critical role in...Regina Liviandari
,
Ari Estuningtyas
,
Kusmardi
,
Linda Erlina
-
Molecular Docking of ftsZ Protein of Staphylococcus aureus to Indonesian Herbal Compound
Microbial resistance to antibiotics is a growing global problem, and new antibacterial agents are needed to overcome this. One of the bacteria with a high level of resistance is Staphylococcus aureus . Herbal...Maria Diyan Monica
,
Linda Erlina
,
Fadilah Fadilah
,
Rafika Indah Paramita
-
Identification of Active Compounds of Leaf Extract and Seed Oil of Moringa oleifera in TrkB Receptor as Neuroprotective by Molecular Docking
The functional ability of the brain will decline progressively during aging which usually involves changes in plasticity. BDNF is one of the neurotrophins that regulates plasticity via TrkB receptors. So the...Muhamad Sadam Safutra
,
Fadilah
,
Wawaimuli Arozal
,
Agian Jeffilano Barinda
-
Distribution of blaCTX-M, blaSHV, blaTEM genes in Extended Spectrum β-Laktamase Producing Klebsiella pneumoniae from Clinical Isolates in Jakarta
Klebsiella pneumoniae is one of the ESKAPE pathogens ( Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa , and Enterobacter spp.) due to their...Yulia Engel
,
Conny Riana Tjampakasari
,
Fithriyah Sjatha
-
The Implementation of Machine Learning Algorithms for Breast Cancer Biomarker Validation in Metabolomics Studies
Breast cancer is a heterogeneous disease characterized by distinct molecular and metabolic characteristics, making its diagnostics and treatment challenging. The existence of metabolic reprogramming in breast cancer...Nindhyana Diwaratri Ratnaningayu
,
Aryo Tedjo
,
Sonar Soni Panigoro
-
Community Attitude Toward The Behavior Of Reducing and Handling Plastic Waste In Water Sweet Beach Area, Padang City
The aim of the study was to describe people's attitudes towards the behavior of reducing and handling plastic waste in the Air Manis Beach area of Padang City. This research method uses a qualitative approach in the...Rira Fauziah Hasibuan
,
Nur Afrainin Syah
,
Ida Rahmah Burhan
-
Mobile Genetic Elements Associated with Third-Generation Cephalosporin Resistance in Klebsiella pneumoniae
Klebsiella  pneumoniae is the Enterobacteriaceae family can be found in the environment, humans and animals. These bacteria are common causes of hospital, community and healthcare associated infections. Third...Yulia Enggel
,
Connny Riana Tjampakasari
,
Ariyani Kiranasari
-
Molecular Viability Assay: Improving Leprosy Diagnosis beyond Current Gold Standard
Neglected tropical diseases are still part of the health problems faced by the world. One of the neglected tropical diseases that has not yet reached 100% elimination is leprosy. Mycobacterium leprae is the...Clara Imaniar
,
Ibnu Agus Ariyanto
,
Yeva Rosana
-
Genome-Wide Association Study for the Identification of Genetic Variants Associated with Facial Skin Phenotypes
Facial skin phenotypes such as pigmentation, wrinkles, and lentigines are determined by genetics and environmental factors. The genetic factor is known as the basic formation of facial skin phenotype variations in...Rusma Yulita
,
Yulia Ariani Aswin
,
Rafika Indah Paramita
-
Flavonoid Role as Autophagy Modulators in Breast Cancer Treatment Strategy
Autophagy is a tightly regulated catabolic process that enables cancer cells to survive under metabolic stress and contributes to the development of chemoresistance. Targeting autophagy has therefore emerged as a...Frans Dany
,
Ade Arsianti
,
Linda Erlina
,
Ratih Rinendyaputri
-
Mobile Genetic Elements Contributing to Carbapenem Resistance in Acinetobacter baumannii: Current Insights
Acinetobacter baumannii has become a major cause of hospital-acquired infections with the rapid development of resistance to multiple antibiotics, including critical carbapenems. This resistance challenge limits...Azzahrah Khairunnisa Mardhiyah
,
Yulia
,
Fithriyah
-
6-Gingerol Slightly Reduces Hepatic Endoplasmic Reticulum Stress Markers in Rats with High-Fat, High-Fructose Diet-Induced Metabolic Syndrome
Metabolic syndrome (MetS) is linked to hepatic endoplasmic reticulum (ER) stress. This study evaluated 6-gingerol’s potential to alleviate ER stress in a high-fat high-fructose (HFHF)-induced MetS rat model. Male...Nouman Ahmad
,
Syarifah Dewi
,
Vivian Soetikno