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  • Biological Activity of Der p 1 and Der f 1 in Allergic Asthma and Their Contribution in Inflammation and the Role of Anti-inflammation in Allergic Asthma

    Asthma is a disease marked by chronic inflammation of the airways, with indications including wheezing, shortness of breath, and/or cough. As reported by GINA, the global prevalence of asthma is 1-18%. One type of...
    Julian Indonesia , Anna Rozaliyani Indonesia , Heri Wibowo Indonesia , Triya Damayanti Indonesia
    Pages: 560-573 2023-12-05
    10.24036/eksakta/vol23-iss04/463
    494 275
  • Algorithm of Time and Frequency Remote Calibration System of SNSU-BSN

    National Measurement Standards-National Standardization Agency of Indonesia (SNSU-BSN) as the National Metrology Institute of Indonesia has provided time and frequency calibration services for customers. Time and...
    A. Mohamad Boynawan Indonesia , Ratnaningsih Ratnaningsih Indonesia , Windi Kurnia P Indonesia , Yulita Ika P Indonesia , Asep Hapiddin Indonesia , Muhammad Azzumar Indonesia
    Pages: 77-84 2020-09-30
    10.24036/eksakta/vol21-iss2/241
    593 413
  • Pharmacophore Modeling, Molecular Docking, and ADMET Approach for Identification of Anti-Cancer Agents Targeting the C-Jun N-Terminal Kinase (JNK) Protein

    One of the most prevalent cancers in Indonesia is breast cancer, based on Indonesia's pathological-based registration.    Breast cancer is a complex, heterogeneous disease classified into...
    Nur Ayu Ramadanti Indonesia , Linda Erlina Indonesia , Rafika Indah Paramita Indonesia , Aryo Tedjo Indonesia , Fadillah Fadillah Indonesia , Surya Dwira Indonesia
    Pages: 99-111 2023-03-30
    10.24036/eksakta/vol24-iss01/391
    707 340
  • Gastrointestinal Dysfunction after Traumatic Brain Injury: Mechanisms Linking The Gut, Inflammation, and the HPA Axis

    Traumatic brain injury (TBI) is a major global health problem that often leads to systemic complications beyond neurological damage, notably gastrointestinal (GI) dysfunction. The mechanisms linking TBI to GI...
    Dwi Hastuti Indonesia , Sri Widia A Jusman Indonesia , Reni Paramita Indonesia
    Pages: 423-439 2025-12-30
    10.24036/eksakta/vol26-iss04/601
    139 118
  • Structure-Based Virtual Screening and Molecular Docking on the Indonesian Herbal Compound as a Promising Insulin Receptor (INSR) Inhibitor to Suppress Tumor Growth

    A healthy cell maintains a homeostasis condition of glucose level, whereas cancer cells do not. Increased glucose uptake is a hallmark of cancer cells that helps them survive, proliferate, and spread. INSR is one of...
    Veronica Hesti Candraningrum Indonesia , Linda Erlina Indonesia , Rafika Indah Paramita Indonesia , Fadillah Fadillah Indonesia , Surya Dwira Indonesia , Jaka Fajar Fatriansyah Indonesia
    Pages: 487-499 2023-12-30
    10.24036/eksakta/vol23-iss04/452
    471 309
  • Identification of Antiviral Compounds against Hepatitis C Virus (HCV) targeting NS3 Protein by Pharmacophore Modeling, Molecular Docking, and ADMET Approach

    Hepatitis C Virus (HCV) is a world health problem. HCV infection is initiated by various structural and non-structural proteins. The HCV NS3 protein has an important function in viral replication. The N-terminal...
    Ratih Rahayu Indonesia , Linda Erlina Indonesia , Suratno Lulut Ratnoglik Indonesia , Andi Yasmon Indonesia , Fadilah Indonesia , Rafika Indah Paramita Indonesia
    Pages: 523-536 2023-12-30
    10.24036/eksakta/vol23-iss04/448
    413 248
  • Ligand Based Pharmacophore Modelling, Virtual Screening, Molecular Docking, and ADMETOX of Natural Compounds as Antibiotic Candidates against Urinary Tract Infections (UTI)

    The use of antibiotic drugs requires close supervision that patients take antibiotics according to the rules. Irregular antibiotic use led to increased ADR cases (Antibiotic Drug-resistant). ADR is when an individual...
    Windy Dwininda Indonesia , Linda Erlina Indonesia , Rafika Indah Paramita Indonesia , Fadillah Fadillah Indonesia , Surya Dwira Indonesia , Jaka Fajar Fatriansyah Indonesia
    Pages: 193-206 2023-06-30
    10.24036/eksakta/vol24-iss02/404
    1198 329
  • The Evolution of Zoonosis-Related Studies in Indonesia, 1977-2023: Bibliometric Analysis Concepts

    Various zoonotic diseases have been reported as epidemics throughout the world, including in Indonesia. Various studies have been conducted related to gaps in knowledge, especially on disease distribution, etiology,...
    Diana Nurjanah Indonesia , Indi Dharmayanti Indonesia , Fadilah Fadilah Indonesia
    Pages: 38-57 2024-03-30
    10.24036/eksakta/vol25-iss01/465
    286 305
  • Data Acquisition System for Exothermic and Endothermic Reaction: A Novel Laboratory Approach in Chemistry Learning

    The determination of exothermic and endothermic reactions using conventional thermometers is often constrained by limitations in visualization and objectivity during practical activities. This study aims to...
    Siti Nuryani Indonesia , Ijang Rohman Indonesia , Miarti Khikmatun Nais Indonesia , Gun Gun Gumilar Indonesia , Muhamad Nurul Hana Indonesia
    Pages: 349-360 2026-06-30
    10.24036/eksakta/vol27-iss03/697
    75 47
  • Hydrogeological Evaluation Based on Water Quality Parameters and Groundwater Level Conditions in Kolaka and Tangketada Basins, Southeast Sulawesi

    This study aims to evaluate the hydrogeological conditions of Pomalaa through analysis of groundwater flow patterns, groundwater level fluctuations, and water quality parameters. The methods used include geological...
    Muhammad Abdul Rahman Salim Indonesia , Dasapta Erwin Irawan Indonesia , Imam A. Sadisun Indonesia , Bonanza Herlambang Indonesia , Kurniawan Indonesia
    Pages: 530-548 2025-12-30
    10.24036/eksakta/vol26-iss04/623
    93 95
  • Peak Ground Acceleration Mapping of Indonesia Using Complementary Area Source and Smoothed Seismicity Approaches

     In Indonesia, the choice between area source and smoothed seismicity approaches has been driven by data availability rather than scientific evaluation, and no systematic comparison of both methods at the national...
    Eka Nioisa Br Surbakti Indonesia , Ardian Saputra Indonesia , Rizki Wulandari Indonesia , Yudha Styawan Indonesia
    Pages: 241-256 2026-06-30
    10.24036/eksakta/vol27-iss03/684
    60 44
  • Exploring the Chemopreventive Potential of Soybean Phytochemicals Targeting BRCA1 Protein: A Molecular Docking Study

    Breast cancer remains a significant cause of cancer-related mortality among women globally, highlighting the importance for preventive strategies targeting early molecular events. BRCA1 plays a critical role in...
    Regina Liviandari Indonesia , Ari Estuningtyas Indonesia , Kusmardi Indonesia , Linda Erlina Indonesia
    Pages: 191-206 2026-04-30
    10.24036/eksakta/vol27-iss02/671
    34 58
  • Study of Indonesian Rhododendron: Classification, Conservation, and Pharmacology Activity

    Rhododendrons are representatives of ornamental plants with a wide range of pharmacological activities. Indonesia is the second richest country in Rhododendron plants with 233 species. Unfortunately, more than 85...
    Damiana Nofita Birhi Indonesia , Meike Tiya Kusuma Indonesia , Antonia Fransiska Laka Indonesia
    Pages: 140-162 2025-06-30
    10.24036/eksakta/vol26-iss02/583
    178 143
  • Anatomy of Cleome rutidosperma DC. (Cleomaceae) Ovary Development in Mataram City

    Cleome rutidosperma is one of the species that belong to famili Cleomaceae and ordo Brassicales.  The purpose of this research is to observe the ovary development of C. rutidosperma and analyse the differences...
    Zuhara Dwi Lestari Indonesia , Quratul Puspa Aeni Indonesia , Zalianty Dwinur Safitri Indonesia , Satria Gunawan Indonesia , Windi Pratami Indonesia , Nur Shopya Affifaturrahmah Indonesia , Suci Miranti Indonesia , Tri Mulyaningsih Indonesia
    Pages: 1-11 2025-03-30
    10.24036/eksakta/vol26-iss01/536
    144 339
  • Analysis of The Effect of Soundproofing on Ship Engines Based on Composite Materials Made from Tofu Dregs (Glycine Max L Merill)

    Minimizing ship noise and vibrations is crucial due to  potentially severe consequences, such as communication problems, sleep disturbances, stress, and structural damage. To address this, effective dampers are...
    Aurista Miftahatul Ilmah Indonesia , Anauta Lungiding Angga Risdianto Indonesia , Belgis Risky Wijaya Indonesia , Arief Syarifuddin Indonesia , Triyanti Irmiyana Indonesia , Taufan Prasetyo Indonesia , Muhammad Arus Samudera Indonesia , Mohammad Hamid Indonesia
    Pages: 302-310 2024-09-30
    10.24036/eksakta/vol25-iss03/436
    181 165
  • Artificial Intelligence-Based E-Learning in Chemistry Learning: A Review of Implementation in High Schools

    This study analyzes the challenges and opportunities for implementing artificial intelligence (AI)-based e-learning in West Sumatra, with global and regional comparisons. Infrastructure gaps are a major obstacle,...
    Rahadian Zainul Indonesia , Dony Novaliendry Indonesia , Budhi Oktavia Indonesia , Fitrah Mey Harmi Siregar Indonesia , Maiti Faddila Indonesia , Hidayatul Husna Indonesia , Delsya Helvira Suci Indonesia
    Pages: 321-333 2024-12-30
    10.24036/eksakta/vol25-iss04/307
    26 28
  • Identification of Active Compounds of Leaf Extract and Seed Oil of Moringa oleifera in TrkB Receptor as Neuroprotective by Molecular Docking

    The functional ability of the brain will decline progressively during aging which usually involves changes in plasticity. BDNF is one of the neurotrophins that regulates plasticity via TrkB receptors. So the...
    Muhamad Sadam Safutra Indonesia , Fadilah Indonesia , Wawaimuli Arozal Indonesia , Agian Jeffilano Barinda Indonesia
    Pages: 151-163 2024-06-30
    10.24036/eksakta/vol25-iss02/442
    245 266
  • Molecular Docking of ftsZ Protein of Staphylococcus aureus to Indonesian Herbal Compound

    Microbial resistance to antibiotics is a growing global problem, and new antibacterial agents are needed to overcome this. One of the bacteria with a high level of resistance is Staphylococcus aureus . Herbal...
    Maria Diyan Monica Indonesia , Linda Erlina Indonesia , Fadilah Fadilah Indonesia , Rafika Indah Paramita Indonesia
    Pages: 1-13 2024-03-30
    10.24036/eksakta/vol25-iss01/431
    346 329
  • Artificial Intelligence in Teacher Soft-Skill Development: A Review of Educational Initiatives in West Sumatra

    This study examines the application of artificial intelligence (AI) in developing teachers' soft skills in West Sumatra. AI technology plays an important role in supporting the improvement of communication skills,...
    Rahadian Zainul Indonesia , Dony Novaliendry Indonesia , Budhi Oktavia Indonesia , Fitrah Mey Harmi Siregar Indonesia , Maiti Faddila Indonesia , Hidayatul Husna Indonesia , Delsya Helvira Suci Indonesia
    Pages: 508-520 2024-12-30
    10.24036/eksakta/vol23-iss02/301
    25 29
  • Effect of Coriander (Coriandrum sativum Lour) Seed-Ethanol Extract on Spermatozoa Quality in Alloxan-Induced Male Rats

    Coriander fruit ( Coriandrum sativum Lour) has long been used and utilized by humans as a medicine to lower blood sugar levels. This study aimed to test the ethanol extract of coriander ( Coriandrum sativum Lour)...
    Irza Haicha Pratama Indonesia , Neka Cahyanda Putri Indonesia , Nuryani Nainggolan Indonesia , Ok Yurizal Indonesia
    Pages: 9-18 2023-03-30
    10.24036/eksakta/vol24-iss01/365
    298 239
  • The Potential of Active Compounds from Melinjo Leaves (Gnetum gnemon) as an Antihistamine using Molecular Docking Approach for Acetylcholine Muscarinic M3 Receptor Inhibition

    Melinjo leaves (Gnetum gnemon) have been used traditionally in Maluku to treat spoilage in the fish product. Melinjo leaves contain secondary metabolites with anti-inflammatory and antibacterial biological...
    Nelson Gaspersz Indonesia , Matthew Adi Honey Amos Indonesia , Yusthinus T. Male Indonesia , Muh. Daswar A. Baharudin Indonesia , Dean Y.E. Leuwol Indonesia , Rahma El Indonesia , Priska M. Pattiasina Indonesia , Mario R. Sohilait Indonesia , Herland Satriawan Malaysia
    Pages: 549-559 2023-12-30
    10.24036/eksakta/vol23-iss04/460
    442 285
  • In Silico Evaluation of Natural Compounds as Dual Inhibitors of Exotoxin A and LasB (Elastase) Virulence Proteins in Pseudomonas aeruginosa

    Pseudomonas aeruginosa is an opportunistic pathogen whose virulence is largely mediated by Exotoxin A and LasB (elastase), making them promising anti-virulence drug targets. This study aimed to evaluate the...
    Andrias Bayu Fariska Indonesia , Linda Erlina Indonesia , Ade Arsianti Indonesia , Aryo Tedjo Indonesia
    Pages: 480-499 2025-12-30
    10.24036/eksakta/vol26-iss04/631
    116 108
  • Clustering Provinces in Indonesia Based on The Main Food Crop Production Using The Spatial Fuzzy C-Means

    Agriculture plays a strategic role in achieving food security in Indonesia. However, the production of major food crops in Indonesia shows uneven distribution, which may affect efforts to achieve food...
    Hazmira Yozza Indonesia , Aldi Mukhlis Indonesia , Maiyastri Indonesia
    Pages: 498-507 2024-12-30
    10.24036/eksakta/vol25-iss04/385
    226 317
  • Synthesis of Nano alfa-Cellulose-Based Bioplastic from Empty Fruit Bunches of Palm Oil

    Cellulose, as a renewable resource, has recently emerged as a primary focus for researchers aiming to develop sustainable biomaterials.  FTIR spectra show that there is no significant difference between them....
    Benny Rio Fernandez Indonesia , Rycce Sylviana Pratikha Indonesia , Sari Farah Dina Indonesia , Poltak Evencus Hutajulu Indonesia , Gimelliya Saragih Indonesia , Dafina Ariza Indonesia , Indah Fitri Ramadhani Indonesia , Yosef Boy Wijaya Sinaga Indonesia
    Pages: 401-414 2026-06-30
    10.24036/eksakta/vol27-iss03/700
    58 30
  • Histopathology of Gills Fish in Rivers Contaminated by Heavy Metals from Artisanal Gold Mining Waste in Lebong Regency, Bengkulu Province

    The aquatic environment is crucial for fish survival because fish require appropriate aquatic environment. Artisanal gold mining generates heavy metal waste in Lebong Regency, polluting the river flows. Heavy metals...
    Dian Fita Lestari Indonesia , Vestidhia Yunisya Atmaja Indonesia , Santi Nurul Kamilah Indonesia , Eliza Febrianti Indonesia , Farisa Retno Indonesia , Hengki Turnando Indonesia , Ibranio Risditama Indonesia
    Pages: 186-200 2025-06-30
    10.24036/eksakta/vol26-iss02/588
    149 194
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