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Biological Activity of Der p 1 and Der f 1 in Allergic Asthma and Their Contribution in Inflammation and the Role of Anti-inflammation in Allergic Asthma
Asthma is a disease marked by chronic inflammation of the airways, with indications including wheezing, shortness of breath, and/or cough. As reported by GINA, the global prevalence of asthma is 1-18%. One type of... -
Algorithm of Time and Frequency Remote Calibration System of SNSU-BSN
National Measurement Standards-National Standardization Agency of Indonesia (SNSU-BSN) as the National Metrology Institute of Indonesia has provided time and frequency calibration services for customers. Time and... -
Pharmacophore Modeling, Molecular Docking, and ADMET Approach for Identification of Anti-Cancer Agents Targeting the C-Jun N-Terminal Kinase (JNK) Protein
One of the most prevalent cancers in Indonesia is breast cancer, based on Indonesia's pathological-based registration.   Breast cancer is a complex, heterogeneous disease classified into... -
Gastrointestinal Dysfunction after Traumatic Brain Injury: Mechanisms Linking The Gut, Inflammation, and the HPA Axis
Traumatic brain injury (TBI) is a major global health problem that often leads to systemic complications beyond neurological damage, notably gastrointestinal (GI) dysfunction. The mechanisms linking TBI to GI... -
Structure-Based Virtual Screening and Molecular Docking on the Indonesian Herbal Compound as a Promising Insulin Receptor (INSR) Inhibitor to Suppress Tumor Growth
A healthy cell maintains a homeostasis condition of glucose level, whereas cancer cells do not. Increased glucose uptake is a hallmark of cancer cells that helps them survive, proliferate, and spread. INSR is one of... -
Identification of Antiviral Compounds against Hepatitis C Virus (HCV) targeting NS3 Protein by Pharmacophore Modeling, Molecular Docking, and ADMET Approach
Hepatitis C Virus (HCV) is a world health problem. HCV infection is initiated by various structural and non-structural proteins. The HCV NS3 protein has an important function in viral replication. The N-terminal... -
Ligand Based Pharmacophore Modelling, Virtual Screening, Molecular Docking, and ADMETOX of Natural Compounds as Antibiotic Candidates against Urinary Tract Infections (UTI)
The use of antibiotic drugs requires close supervision that patients take antibiotics according to the rules. Irregular antibiotic use led to increased ADR cases (Antibiotic Drug-resistant). ADR is when an individual... -
The Evolution of Zoonosis-Related Studies in Indonesia, 1977-2023: Bibliometric Analysis Concepts
Various zoonotic diseases have been reported as epidemics throughout the world, including in Indonesia. Various studies have been conducted related to gaps in knowledge, especially on disease distribution, etiology,... -
Data Acquisition System for Exothermic and Endothermic Reaction: A Novel Laboratory Approach in Chemistry Learning
The determination of exothermic and endothermic reactions using conventional thermometers is often constrained by limitations in visualization and objectivity during practical activities. This study aims to... -
Hydrogeological Evaluation Based on Water Quality Parameters and Groundwater Level Conditions in Kolaka and Tangketada Basins, Southeast Sulawesi
This study aims to evaluate the hydrogeological conditions of Pomalaa through analysis of groundwater flow patterns, groundwater level fluctuations, and water quality parameters. The methods used include geological... -
Peak Ground Acceleration Mapping of Indonesia Using Complementary Area Source and Smoothed Seismicity Approaches
In Indonesia, the choice between area source and smoothed seismicity approaches has been driven by data availability rather than scientific evaluation, and no systematic comparison of both methods at the national... -
Exploring the Chemopreventive Potential of Soybean Phytochemicals Targeting BRCA1 Protein: A Molecular Docking Study
Breast cancer remains a significant cause of cancer-related mortality among women globally, highlighting the importance for preventive strategies targeting early molecular events. BRCA1 plays a critical role in... -
Study of Indonesian Rhododendron: Classification, Conservation, and Pharmacology Activity
Rhododendrons are representatives of ornamental plants with a wide range of pharmacological activities. Indonesia is the second richest country in Rhododendron plants with 233 species. Unfortunately, more than 85... -
Anatomy of Cleome rutidosperma DC. (Cleomaceae) Ovary Development in Mataram City
Cleome rutidosperma is one of the species that belong to famili Cleomaceae and ordo Brassicales. The purpose of this research is to observe the ovary development of C. rutidosperma and analyse the differences... -
Analysis of The Effect of Soundproofing on Ship Engines Based on Composite Materials Made from Tofu Dregs (Glycine Max L Merill)
Minimizing ship noise and vibrations is crucial due to potentially severe consequences, such as communication problems, sleep disturbances, stress, and structural damage. To address this, effective dampers are... -
Artificial Intelligence-Based E-Learning in Chemistry Learning: A Review of Implementation in High Schools
This study analyzes the challenges and opportunities for implementing artificial intelligence (AI)-based e-learning in West Sumatra, with global and regional comparisons. Infrastructure gaps are a major obstacle,... -
Identification of Active Compounds of Leaf Extract and Seed Oil of Moringa oleifera in TrkB Receptor as Neuroprotective by Molecular Docking
The functional ability of the brain will decline progressively during aging which usually involves changes in plasticity. BDNF is one of the neurotrophins that regulates plasticity via TrkB receptors. So the... -
Molecular Docking of ftsZ Protein of Staphylococcus aureus to Indonesian Herbal Compound
Microbial resistance to antibiotics is a growing global problem, and new antibacterial agents are needed to overcome this. One of the bacteria with a high level of resistance is Staphylococcus aureus . Herbal... -
Artificial Intelligence in Teacher Soft-Skill Development: A Review of Educational Initiatives in West Sumatra
This study examines the application of artificial intelligence (AI) in developing teachers' soft skills in West Sumatra. AI technology plays an important role in supporting the improvement of communication skills,... -
Effect of Coriander (Coriandrum sativum Lour) Seed-Ethanol Extract on Spermatozoa Quality in Alloxan-Induced Male Rats
Coriander fruit ( Coriandrum sativum Lour) has long been used and utilized by humans as a medicine to lower blood sugar levels. This study aimed to test the ethanol extract of coriander ( Coriandrum sativum Lour)... -
The Potential of Active Compounds from Melinjo Leaves (Gnetum gnemon) as an Antihistamine using Molecular Docking Approach for Acetylcholine Muscarinic M3 Receptor Inhibition
Melinjo leaves (Gnetum gnemon) have been used traditionally in Maluku to treat spoilage in the fish product. Melinjo leaves contain secondary metabolites with anti-inflammatory and antibacterial biological... -
In Silico Evaluation of Natural Compounds as Dual Inhibitors of Exotoxin A and LasB (Elastase) Virulence Proteins in Pseudomonas aeruginosa
Pseudomonas aeruginosa is an opportunistic pathogen whose virulence is largely mediated by Exotoxin A and LasB (elastase), making them promising anti-virulence drug targets. This study aimed to evaluate the... -
Clustering Provinces in Indonesia Based on The Main Food Crop Production Using The Spatial Fuzzy C-Means
Agriculture plays a strategic role in achieving food security in Indonesia. However, the production of major food crops in Indonesia shows uneven distribution, which may affect efforts to achieve food... -
Synthesis of Nano alfa-Cellulose-Based Bioplastic from Empty Fruit Bunches of Palm Oil
Cellulose, as a renewable resource, has recently emerged as a primary focus for researchers aiming to develop sustainable biomaterials. FTIR spectra show that there is no significant difference between them.... -
Histopathology of Gills Fish in Rivers Contaminated by Heavy Metals from Artisanal Gold Mining Waste in Lebong Regency, Bengkulu Province
The aquatic environment is crucial for fish survival because fish require appropriate aquatic environment. Artisanal gold mining generates heavy metal waste in Lebong Regency, polluting the river flows. Heavy metals...