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  • Study of Ordinal Regression Method for Supporting Factors Investigation in Stages Condition of Breast Cancer Patients in Dr. Soetomo Surabaya Hospital, Indonesia

    Dr. Soetomo Surabaya Hospital in 2019 received 167,000 cancer patients, and the highest was breast cancer. The increase in the stage of breast cancer is caused by the size of the tumor and how widely the cancer cells...
    Thania Muhammad Indonesia , Destri Susilaningrum Indonesia , Vidi Vianney C.M.Tanggo Indonesia
    Pages: 220-229 2021-09-30
    10.24036/eksakta/vol22-iss3/281
    301 185
  • Pharmacophore Modeling, Molecular Docking, and ADMET Approach for Identification of Anti-Cancer Agents Targeting the C-Jun N-Terminal Kinase (JNK) Protein

    One of the most prevalent cancers in Indonesia is breast cancer, based on Indonesia's pathological-based registration.    Breast cancer is a complex, heterogeneous disease classified into...
    Nur Ayu Ramadanti Indonesia , Linda Erlina Indonesia , Rafika Indah Paramita Indonesia , Aryo Tedjo Indonesia , Fadillah Fadillah Indonesia , Surya Dwira Indonesia
    Pages: 99-111 2023-03-30
    10.24036/eksakta/vol24-iss01/391
    686 331
  • The Implementation of Machine Learning Algorithms for Breast Cancer Biomarker Validation in Metabolomics Studies

    Breast cancer is a heterogeneous disease characterized by distinct molecular and metabolic characteristics, making its diagnostics and treatment challenging. The existence of metabolic reprogramming in breast cancer...
    Nindhyana Diwaratri Ratnaningayu Indonesia , Aryo Tedjo Indonesia , Sonar Soni Panigoro Indonesia
    Pages: 468-483 2024-12-30
    10.24036/eksakta/vol25-iss04/553
    172 202
  • Flavonoid Role as Autophagy Modulators in Breast Cancer Treatment Strategy

    Autophagy is a tightly regulated catabolic process that enables cancer cells to survive under metabolic stress and contributes to the development of chemoresistance. Targeting autophagy has therefore emerged as a...
    Frans Dany Indonesia , Ade Arsianti Indonesia , Linda Erlina Indonesia , Ratih Rinendyaputri Indonesia
    Pages: 440-455 2025-12-30
    10.24036/eksakta/vol26-iss04/624
    71 69
  • Connecting the Dots: Transcriptomic Approaches and Relationship between Myocardial Infarction and Breast Cancer

    Myocardial infarction, resulting from coronary blood vessel blockage, inflicts lasting damage on the heart muscle. Meanwhile, breast cancer ranks among the most diagnosed cancers, causing millions of deaths annually....
    Miftahul Khair Akbar Indonesia , Fadilah Fadilah Indonesia , Arief Aulia Rahman Indonesia
    Pages: 111-125 2024-03-30
    10.24036/eksakta/vol25-iss01/478
    216 155
  • Exploring the Chemopreventive Potential of Soybean Phytochemicals Targeting BRCA1 Protein: A Molecular Docking Study

    Breast cancer remains a significant cause of cancer-related mortality among women globally, highlighting the importance for preventive strategies targeting early molecular events. BRCA1 plays a critical role in...
    Regina Liviandari Indonesia , Ari Estuningtyas Indonesia , Kusmardi Indonesia , Linda Erlina Indonesia
    Pages: 191-206 2026-04-30
    10.24036/eksakta/vol27-iss02/671
    23 44
  • In Silico Evaluation of Bisbenzylisoquinoline Compounds from Stephania sp. as EGFR Inhibitors for Triple-Negative Breast Cancer

    Triple-negative breast cancer (TNBC) represents a highly aggressive breast malignancy subtype characterized by constrained therapeutic alternatives and poor clinical outcomes. Since Epidermal Growth Factor Receptor...
    Amanda Triastuti Amanda Indonesia , Denny Satria Indonesia
    Pages: 231-240 2026-04-30
    10.24036/eksakta/vol27-iss02/677
    20 30
  • In Silico Evaluation of Cardiac Glycosides from Vernonia amygdalina as EGFR Inhibitors in Triple Negative Breast Cancer

    Triple-negative breast cancer (TNBC) is an aggressive subtype with limited targeted therapies, emphasizing the urgent need for novel molecular inhibitors. Epidermal growth factor receptor (EGFR) is overexpressed in...
    Gisela Agustin Habayahan Indonesia , Denny Satria Indonesia
    Pages: 219-230 2026-04-30
    10.24036/eksakta/vol27-iss02/676
    21 29
  • Integrative Transcriptomic and Docking Analysis of Coffee Bioactives Targeting CCNA2, AKT1, and CDK2 in TNBC

    Triple-negative breast cancer (TNBC) is an aggressive breast cancer subtype characterized by high proliferation rates, poor prognosis, and limited therapeutic options. Coffee-derived bioactive compounds have...
    Ida Neni Haryanti Indonesia , Linda Erlina Indonesia , Ade Arsianti Indonesia , Aryo Tedjo Indonesia
    Pages: 578-597 2026-07-31
    10.24036/eksakta/vol27-iss04/707
    36 21
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