Main Article Content


This study used catfish Clarias gariepinus as an experimental animal, which given supplementation of curcumin and thyroxine hormone. The results showed that during the reproductive period there was an increase in body weight of female catfish in line with the development of the gonads. Through the histology of the gonads, it appeared that oocyte development occurs over time.  The results of liver histology showed a high activity of hepatocyte cells as indicated by the formation of vacuoles, as the storage site for vitellogenin, in their cytoplasm. Supplementation of curcumin and thyroxine was able to increase the specific growth rate of catfish, and the catfish group that given the combination treatment of curcumin supplementation (5 of feed) with thyroxine hormone (0.1 of feed) showed the more optimal results.


Clarias gariepinus curcumin Histology SGR Thyroxine

Article Details

How to Cite
Rawung LD, Sunarma A, Rayer DJJ. The Specific Growth Rate (SGR) Related to the Histology of Gonad and Liver of African Catfish (Clarias gariepinus) Supplemented with Curcumin and Thyroxine Hormone. Eksakta [Internet]. 2021May14 [cited 2021Jun.12];22(2):154-61. Available from:


  1. Dewi, C.D; Manalu, W; Ekastuti, D.R; Sudrajat, A.O. (2018). The role of the turmeric powder supplementation in improving liver performance to support the production of siam catfish (Pangasianodon hypophthalamus). Omni-Akuatika,14(1), 44-53.
  2. Rawung, L.D; Ekastuti, D.R; Sunarma, A; Junior, M.Z; Rahminiwati, M; Manalu, W. (2021). Effectivity of Curcumin and Thyroxine Supplementations for Improving Liver Functions to Support Reproduction of African Catfish (Clarias gariepinus). Jordan J. Biol. Sci. Volume 14, Nomor 1.
  3. Kasiyati. (2017). Sulementasi Kurkumin dan Peran Cahaya Monokromatik untuk Mengoptimalkan Biosintesis Telur Itik Lokal. Disertasi, Institut Pertanian Bogor, Bogor.
  4. Bancroft JD, Gamble M.(2008). Theory and practice of histological techniques. 6thed. Churchill Livingstone, Elsevier, China.
  5. Anand, P; Sundaram, C; Jhurani, S; Kunnumakkara, A.B; Aggarwal, B.B. (2008). Curcumin and cancer: An “old-age” disease with and “age-old” solution. Cancer letters : 267, 133-164.
  6. Bachmeier, B.E; Mirisola, V; Romeo, F; Generoso, L; Esposito, A; Dell’Eva, R; Blengio, F; Killian, P.H; Albini, A; Pfeffer, U. (2010). Reference profile correlation reveals estrogen-like transcriptional activity of curcumin. Cell Physiol Biochem, 26, 471-482.
  7. Zhao, S.G; Li, Q; Liu, Z.X; Wang, J.J; Wang, X.X; Qin, M; Wen, Q.S. (2011). Curcumin attenuates insulin resistance in hepatocytes by inducing Nrf2 nuclear translocation. Hepatogastroenterology, 58 (112), 2106-2111.
  8. Dewi, C.D; Ekastuti, D.R; Sudrajat, A.O; Manalu, W. (2018). Improved vitellogenesis, gonad development and egg diameter in catfish (Panasianodon hypophthalmus) supplemented with turmeric (Curcuma longa) powder. Aquac. Res, 49(2), 651-658.
  9. Rawung L.D; Saruan J. (2020). Effectiveness of curcumin supplementation in feed on liver productivity and reproductive performance of female carp Cyprinus carpio L. Indonesian Biodiversity Journal, 1(1), 22-33
  10. Rawung, L.D; Ekastuti, D.R; Junior, M.Z; Rahminiwati, M; Sunarma, A; Manalu, W. (2020). Reproductive performances and egg qualities in African catfish (Clarias gariepinus) broodstocks supplemented with curcumin and thyroxine hormone. Omni-Akuatika, 16(1), 32-47.
  11. Kasiyati; Sumiati; Ekasturi, D.R; Manalu, W. (2016). Roles of curcumin and monochromatic light in optimizing liver function to support egg yolk biosynthesis in magelang duck. Int Poult Sci, 15, 414-424.
  12. Saraswati, T.R; Manalu, W; Ekastuti, D.R; Kusumorini, N. (2013). Increased egg production of Japanese quil (Cortunix japonica) by improving liver function through turmeric powder supplementation. Int J Poult Sci, 12(10), 601-614.
  13. Guyton, A.C; Hall, J.E. (2006). Textbook of medical physiology, eleventh edition. Elsevier Saunders. Pennsylvania.
  14. Ayson, F.G; Lam, T.J. (1993). Thyroxine injection of female rabbitfish (Siganus guttatus) broodstock: changes in thyroid hormone levels in plasma, eggs, and yolk-sac larvae, and its effect on larval growth and survival. Aquaculture, 109(1), 83-93.
  15. Agusnimar; Rosyadi. (2015). Pertumbuhan dan kelangsungan hidup ikan selais Kryptopterus lais yang diberi hormone tiroksin. JAI, 14(1), 38-41
  16. Zairin, M.Jr; Pahlawan, R.G; Raswin, M. (2005). Pengaruh pemberian hormone tiroksin secara oral terhadap pertumbuhan dan kelangsungan hidup ikan Platali Koral Xiphophorus maculates. JAI, 4, 31-35
  17. Zenneveld, N; Huisman, E.A; Boon, J.H. (1991). Prinsip-prinsip budidaya ikan. PT. Gramedia Pustaka Umum, Jakarta.
  18. Rawung, L.D; Ekastuti, D.R; Rahminiwati, M; Sunarma, A; Junior, M.Z; Manalu, W. (2019). The blood chemistry profile of African catfish (Clarias gariepinus) Broodstock that supplemented with curcumin and thyroxine hormone during vitellogenesis. Int. J. Sci: Basic Appl Res, aaa48(4), 213-223.
  19. Revathi, P; Iyapparaj, P; Munuswamy, N; Krishnan, M. (2012). Vitellogenesis during the ovarian development in freshwater female prawn Macrobrachium rosenbergii (De Man). Int. J. Aqu. Sci. 3(2), 13-27.